There is one great remedy called “Retinoic ointment” that effectively treats and eliminates the causes of acne. What is this? Do you know where the fattest parts on your face? That’s right, this is mid- face, especially the nose, forehead and chin. But on the body they are chest, shoulders and land on the back between the shoulder blades. And why not? Because in these areas are large number of large sebaceous glands. Sebum is congesting near excretory duct working as a plug.
How to deal with it? Fighting with acne requires patience ! A cardinal rule – cleanliness. Very good when washing the face to use a special liquid soap for oily skin. The second rule – do not touch face with her hands endlessly not squeeze acne as soon as the sight would be a mirror. Well, of course, for the treatment of acne require special medication. There are many expensive cosmetics, the use of which reduces inflammation, but this approach gives only a short-term effect. Acne appear again soon ! There is one great tool ” Retinoic ointment “, which effectively treats and attack the causes of acne. Use it is very simple : you need to apply a thin layer of cream on cleansed skin 1-2 times a day. And so it goes from 4 to 12 weeks. Retinoic ointment ! No chance for acne to
Pharmacological properties of Tretinoin Cream 025
Of course, tretinoin cream 0.25 is primarily intended for the treatment of acne ! But for a long time on many websites there are discussions about the rejuvenation of the skin with it. Is there any sense in using this ointment ? Yes, there is! In 13 -cis – cream, which is part of retinoic ointment has two important properties which are almost not used in the treatment of acne.
First – penetrating deep into the skin, it rearranges fibroblasts cells that produce collagen, elastic fibers, and the substance that fills the space there between. You know that the aging process of the skin the most important participants in collagen and elastic fibers. To them we owe these properties of the skin, as the elasticity, resilience, the ability to quickly spread skin folds. We all want to have a skin like a child, and she characterized by an abundance of intercellular and interfibrillar substance, nice and fast formation of young fibers. So, tretinoin cream 0.25 causes the fibroblasts to work as a child to produce a large number of young collagen and intercellular substance. Of course, such an action can’t be infinite, however, a few months it’s real!
The second application of the second week of reaction comes irritation skin reddens slightly itchy, scaly and sweat profusely. All reaction lasts an average week. Of course, young people this annoying side effect, but if you look at the reaction from the position of those over 30, then surely it’s a real peeling ! Skin after the peeling looks younger and smoother, improves the complexion. Of course, unfortunate that not for life, but for some time.
Application of tretinoin cream 0.25 was conducted against the background of general therapy : 20% solution of sodium hypo intravenously, vitamins B1 and B6 intramuscularly in alternation, purified sulfur, antibiotic therapy, taking into account the sensitivity of flora, staphylococcal toxoid or antifagin scheme. In the treatment of patients with a history of allergic history included antihistamines. Outdoor therapy, along with retinoic ointment included aniline solutions ichthyic tortillas.
Ointment was applied to a thin layer on limited areas of the skin (skin of the face, some patients back, chest) 2 times a day for 20-30 minutes after washing. Duration of treatment is 4-6 weeks. Evaluation of the clinical efficacy and tolerability of retinoic ointment was conducted on the dynamics of changes in clinical signs of disease.
In patients with papules, pustular acne form disease duration from 1 year to 5 years were observed 10 people. Prior therapy : in 6 patients – cleaning, masks, blur cosmetic alcohols ; at 3 – use of vitamins, sulfur, sodium hypophosphite, antibiotics, staphylococcal toxoid autologous ; 1 patient was treated nowhere. Application of ointments retinoic started with the lowest concentration of 0.01 %, in a subsequent good tolerability of retinoic acid concentration was increased to 0.05 % for women and 0.1 % – in men.
In the first week of treatment there was a pronounced effect noted in any patient. After 14 days, a significant improvement and improved ascertained 7 patients, improvement – at 2, no effect – 1 patient. Treatment effect was independent of age and sex of patients.
During treatment at 3.5 weeks in two patients (1 woman and 1 man) marked side effects in the form of strengthening erythema on the face and pronounced itching. Cancel retinoic ointment, antihistamines appointment and replacement of external therapy allowed 2 days to resolve the arisen changes.
In patients with a form of acne conglobata observed one woman and nine men ; disease duration from 2 to 6 years ; age of patients from 18 to 25 years. The process has been presented with multiple comedones inflammatory reaction around them, cystic elements up to 1.5 cm, nodes located in the deep parts of the skin up to 1 cm, painful infiltrates around the outbreaks. Part of nodes opened, with the release of thick pus. In 7 of the 10 patients in the former lesions were severe scarring. Eruptions were on the face and back in 6 patients, three patients – only on the face, one patient solely on skin back. Previously treated as outpatients 6 patients (antibiotics, cleaning, opening units, liquid nitrogen), 4 patients were treated in specialized hospitals complex methods with short periods of clinical remission.
Tretinoin cream 0.25 was administered two times a day to those areas where there was no active rejection of pus, and dissected nodes. During the first week, some positive changes were observed in 3 patients, in 2 weeks – in 6 patients. After 21 days, reducing the intensity of erythema in areas of infiltrates, reducing the formation of new comedones and pustular elements were observed in all patients. Side effects and complications from the use of retinoic ointment were observed. Dependence of the effect of gender and age is not established.
Among patients with seborrhea and seborrheic dermatitis were 2 women and 7 men. Disease duration of 2-8 years. In 7 patients, seborrhea proceeded on the mixed type. While on the face were observed layering large scales yellowish color on a background of erythema, many comedones on the nose, chin, cheeks. On the scalp – peeling, erythema. Patients bother itching. In two patients, in addition, marked seborrheic alopecia.
After 7 days, a significant improvement was achieved in one patient response – in 4 patients. After 14 days, the corresponding effects observed in patients 2 and 7. Improvement was reflected in a decrease in the intensity of erythema, peeling reduction. After 21 days, 1 patient achieved clinical cure, and 5 – survived only minor flaking of the scalp and in the nasolabial triangle, in 3 – peeling was significant. After treatment, the clinical improvement was achieved in 4 patients (44,4 %), marked improvement in 4 (44.4 %), the improvement – 1 patient. Depending on the treatment effect of gender and age is not established.
Deviations were observed in clinical and biochemical blood tests, urinalysis after applying tretinoin cream.